Symantec have release 12.1.6 MP1 (12.1 RU6 MP1).
This version of Symantec Endpoint Protection includes new features in the following areas:
The Symantec Endpoint Protection client adds support for Windows 10.
Symantec Endpoint Protection Manager adds database support for SQL Server 2012 SP2.
Symantec Endpoint Protection Manager adds browser support for Google Chrome through 43.0.2403.107, and for Firefox through 39.0.
Relevant information/articles for upgrade and defect fixes links are included below
New fixes in Symantec Endpoint Protection 12.1.6.1http://www.symantec.com/docs/TECH231856
Upgrade or migrate to Symantec Endpoint Protection 12.1.6 or 12.1.6.1 What's new in Symantec Endpoint Protection 12.1.6 MP1